Effect of β-cyclodextrin complexation on solubility and enzymatic hydrolysis rate of icariin
نویسندگان
چکیده
منابع مشابه
Effect of β-Cyclodextrin Complexation on Solubility and Enzymatic Conversion of Naringin
In the present paper, the effect of beta-cyclodextrin (beta-CD) inclusion complexation on the solubility and enzymatic hydrolysis of naringin was investigated. The inclusion complex of naringin/beta-CD at the molar ratio of 1:1 was obtained by the dropping method and was characterized by differential scanning calorimetry. The solubility of naringin complexes in water at 37 ± 0.1 °C was 15 times...
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Efavirenz belongs to Class II under BCS and exhibit low and variable bioavailability due to its poor aqueous solubility. As such it needs enhancement in the dissolution rate and bioavailability to derive its maximum therapeutic efficacy. The objective of the present investigation is to study the complexation of efavirenz with two cyclodextrins, βcyclodextrin (βCD) and hydroxypropyl β-cyclodextr...
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ژورنال
عنوان ژورنال: Journal of Natural Science, Biology and Medicine
سال: 2013
ISSN: 0976-9668
DOI: 10.4103/0976-9668.107291